Quantification of Drug Molecules in Live Single Cells Using the Single-Probe Mass Spectrometry Technique
نویسندگان
چکیده
منابع مشابه
Live single-cell mass spectrometry.
The history from bio-imaging to live single-cell mass spectrometry (MS) is herein reviewed. The limitation of the current bio-imaging method is probing only known molecules, and a method for finding new molecules is needed for cells which, however, show individual behaviors even in the same incubation dish. Single-cell MALDI-TOF/MS has been developed, but it can detect only molecules that can b...
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2019
ISSN: 0003-2700,1520-6882
DOI: 10.1021/acs.analchem.9b01311